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Amyloidosis 2027: Diagnostic Dilemmas, Biological Insights, and the Next Generation of Treatment

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Add to Calendar Amyloidosis 2027: Diagnostic Dilemmas, Biological Insights, and the Next Generation of Treatment 2/27/2027 7:15:00 AM 2/27/2027 4:20:00 PM America/Chicago For More Details: https://washu.cloud-cme.com/WashUAmyloidosis2027 Description: Amyloidosis 2027: Diagnostic Dilemmas, Biological Insights, and the Next Generation of Treatment is planned and implemented interprofessionally by physicians, pharmacists, nurse practitioners, and nurses. This activity is designed for cardiologists, hematologists, oncologists, nephrologists, neurologists, gastroenterologists, pathologists, hospitalists, internists, family and general medicine physicians, pharmaci... EPNEC - Eric P. Newman Education Center, 320 S. Euclid Ave. false MM/DD/YYYY


Date & Location
Saturday, February 27, 2027, 7:15 AM - 4:20 PM, EPNEC - Eric P. Newman Education Center, 320 S. Euclid Ave., St. Louis, MO

Target Audience
Specialties - Anatomic and Molecular Pathology, Cardiology, Diagnostic Radiology, Family Medicine, Gastroenterology, General Medicine, Geriatrics, Hematology/Oncology, Hospital Medicine, Immunobiology, Internal Medicine, Medical Genetics, Medical Physics, Nephrology, Neurology, Nuclear Medicine, Nuclear Radiology, Nutrition/Dietetics, Oncology, Palliative Medicine, Pathology, Pulmonology, Radiology
Professions - Nurse, Nurse Practitioner, Pharmacist, Physician

Credits
AMA PRA Category 1 Credits™ (6.00 hours), ACPE Contact Hours (6.00 hours), ANCC Contact Hours (6.00 hours), IPCE Credits (6.00 hours), Non-Physician Participation - AMA PRA Category 1 Credit™ Designated Activity (6.00 hours)

Overview
Amyloidosis 2027: Diagnostic Dilemmas, Biological Insights, and the Next Generation of Treatment is planned and implemented interprofessionally by physicians, pharmacists, nurse practitioners, and nurses. This activity is designed for cardiologists, hematologists, oncologists, nephrologists, neurologists, gastroenterologists, pathologists, hospitalists, internists, family and general medicine physicians, pharmacists, nurse practitioners, and nurses,and may be of interest to physician assistants and other that care for these patients. This 6-hour course will provide education through lectures, patient case presentations, a patient journey presentation, panel discussions, and question & answer sessions. The activity will highlight best practices across the recognition, diagnosis, imaging, and treatment of ATTR and AL amyloidosis, including emerging therapies, multidisciplinary supportive care, and access to therapy. The goal of this activity is to enhance knowledge, skillsstrategy, performance, and patient care. Patients, families, and caregivers are invited to attend at no charge, with a non-CME question-and-answer session following the CME program.

Objectives
At the conclusion of this activity, learners will be able to:

  1. Identify the patient populations in which amyloidosis remains underrecognized, and describe the clinical and structural drivers of diagnostic delay.
  2. Interpret mass spectrometry amyloid typing reports, including the significance of bystander proteins, and distinguish amyloidosis from granulomatous and other infiltrative mimics.
  3. Apply a systematic approach to interpreting the serum free light chain assay, including in chronic kidney disease, and to assessing hematologic and organ response in AL amyloidosis.
  4. Describe the biology of the inflammatory and fibrotic myocardial response in ATTR cardiomyopathy and its relationship to heart failure severity.
  5. Compare approved disease modifying therapies for ATTR cardiomyopathy, and apply a structured framework for monitoring disease progression and considering management changes.
  6. Summarize the ongoing and planned trial landscape in ATTR and AL amyloidosis, including gene editing, nearcomplete silencing, amyloid depletion, and Tcell redirecting therapy.
  7. Manage the cardiovascular, renal, gastrointestinal, and neuromuscular consequences of systemic amyloidosis beyond amyloiddirected therapy.
  8. Describe practical strategies for initiating and maintaining amyloiddirected therapy, including prior authorization, insurance, and financialassistance navigation.
  9. Describe the role of advanced imaging, including scintigraphy, cardiac magnetic resonance with extracellular volume, and PET, in diagnosing amyloidosis and tracking response to treatment.
  10. Describe approaches to identifying and delivering amyloidosis care for Veterans within the Veterans Affairs health system.

Registration

Patient & Family Registration 

Please use the link below to registrer, please register each attendee separately.

Amyloidosis 2027: Patient & Family Members Registration

Registration will be available until February 26, 2027, 12:00pm CT.  

Healthcare Provider Registration 

Please regsiter by clicking the Black Register button at the top of the page

Registration information will be available and open soon, please check back.

If you have any questions regarding the course or registration please contact Michelle Padgett at [email protected]

Fees includes enrollment, continuing education credits, educational materials, continental breakfast, lunch and refreshment breaks (paid registrants only).

*** IMPORTANT NOTE for Employees of industry (e.g., pharmaceutical & device companies): DO NOT REGISTER HERE. Please email [email protected] for pre-approval for attendance at this course. Should you register without pre-approval, your registration will be cancelled and refunded less a $25 administrative fee.

Registration/Payment Policy: Your full payment in advance completes your registration and ensures your enrollment in this course. 

Cancellations: Registration fee less $25 administrative charge is refundable if cancellation is received in writing by emailing [email protected] by February 17, 2027. Registration fees are not transferable.

Minimum and Maximum Enrollments Have Been Established.

General Information

Course Information:  Saturday night prior to the course, an email with directions to the online syllabus and onsite information will be sent to the email address utilized to register for the event.

Location: Eric P. Newman Education Center (EPNEC), 320 S. Euclid Ave., St. Louis, Missouri 63110.  It is recommended that you bring a jacket or sweater as meeting room temperatures are difficult to regulate to everyone's preference.

Parking: Validation provided for paid registrants who self-park in the Metro Parking Garage. Overnight parking cannot be validated. Click  Directions/Parking for more information.


Accreditation

In support of improving patient care, Washington University School of Medicine in St. Louis is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.


Credits Available for this Activity:


American Medical Association (AMA)
Washington University School of Medicine in St. Louis designates this live format for a maximum of 6 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

American Nurses Credentialing Center (ANCC)
Washington University School of Medicine in St. Louis designates this live format for a maximum of 6 ANCC contact hours.

Accreditation Council for Pharmacy Education (ACPE)
This activity is approved for a maximum of 6 knowledge-based contact hours (.6 CEUs) in states that recognize ACPE. Participants should only claim credit commensurate with the extent of their participation in the activity. Unique Universal Activity Number JA0000340-0000-27-003-L01-P.  To be awarded credit, attendees must sign in, provide their NABP ePID number and date of birth.

Interprofessional Continuing Education (IPCE)This activity was planned by and for the healthcare team, and learners will receive 6 Interprofessional Continuing Education (IPCE) credits for learning and change.


American Board of Internal Medicine Maintenance of Certification (ABIM MOC)
Successful completion of the CME activity, which includes participation in the evaluation component, enables the participant to earn up to 6 MOC points in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider's responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC.


Additional Information

Cancellation Policy

The cancellation cut-off dates and fees are specific to each course. Refer to the cancellation policy on the individual course page. Please send cancellation requests to [email protected].

WashU Medicine CME reserves the right to cancel or postpone this program if necessary; in the event of cancellation, course fees will be fully refunded. We are not responsible for other costs incurred, such as non-refundable airline tickets or hotel penalties.

Accessibility Statement

This meeting is conducted in accordance with the requirements of the Americans with Disabilities Act (ADA) and applicable regulations.
Individuals who require accommodations to participate are encouraged to submit a written request as early as possible, but no later than ten (10) business days prior to the seminar date, to allow sufficient time to arrange appropriate accommodations. Requests received after this deadline will be reviewed and a good faith effort will be made to provide reasonable accommodations to the extent feasible.



Keywords: LIVEMOCNonPhysAMAANCCACPEABIM MOC

Suggested Hotel Accommodations: 

The Chase Park Plaza Royal Sonesta St. Louis
212 N Kingshighway Blvd, St. Louis, MO 63108
Room Rate: $194 + tax 
The cutoff for the room block is Tuesday, January 27, 2027.

  • Web: https://book.passkey.com/go/WashUAmyloidosisSymposium 

  • By phone: Reservations phone number is 1-314-633-3001

Doubletree by Hilton St. Louis Forest Park
Adjacent to the conference center:
4550 Forest Park Ave., St. Louis, MO 63110
Make your hotel reservations directly with the hotel:
By phone at 314-256-7777.  Ask for the Washington University Visitor rate.
Online at  https://www.hilton.com/en/hotels/stlpkdt
Enter Code #3209101 under “special rate corporate"

AC Hotel St. Louis - Central West End
215 York Avenue, St. Louis MO 63108
314.367.2566  
Washington University Rate: $148 per night + tax
Use this link to make reservations:
Washington University School of Medicine - AC Hotel Reservations

Please Note: Washington University is not responsible for airline, hotel reservations or any other travel expenses. Please confirm registration acceptance prior to purchase of non-refundable or penalty airline tickets.

Transportation:
•    Taxis from the airport are approximately $40.
•    Uber and Lyft are also available.

Washington University School of Medicine in St. Louis School of Medicine adheres to ACCME Criteria, Standards and Policies regarding industry support of continuing medical education. Disclosure of faculty and their commercial relationships will be made prior to the activity.

Mitigation of Relevant Financial Relationships

Washington University School of Medicine in St. Louis adheres to the ACCME’s Standards for Integrity and Independence in Accredited Continuing Education. Any individuals in a position to control the content of a CE activity, including Faculty, planners, reviewers, or others are required to disclose all relevant financial relationships with ineligible entities (commercial interests). All relevant conflicts of interest have been mitigated prior to the commencement of the activity.

Member Information
Role in activity
Nature of Relationship(s) / Name of Ineligible Company(s)
Keith E. Stockerl-Goldstein, MD
Professor of Medicine
WashU Medicine
St. Louis, MO
Co-Director, Faculty
Grant or research support-AstraZeneca Pharmaceuticals LP|Grant or research support-Caelum Biosciences, Inc.|Grant or research support-Genentech Inc|Grant or research support-GlycoMimetics Inc|Grant or research support-Janssen Research & Development LLC|Grant or research support-Nexcella Inc
Molly Rater, MSN
Nurse Practitioner
WashU Medicine
St. Louis, MO
Co-Director, Faculty, Peer Reviewer
Nothing to disclose
Joshua D. Mitchell, MD, MSCI, FACC, FIC-OS
Associate Professor of Medicine
WashU Medicine
St. Louis, MO
Course Director, Faculty
Other relevant financial or material interests-Alnylam Pharmaceuticals Inc (*)|Other relevant financial or material interests-AstraZeneca (*)|Other relevant financial or material interests-BridgeBio Pharma (*)|Other relevant financial or material interests-Pfizer Inc (*)|Grant or research support-Jazz Pharmaceuticals|Grant or research support-Alnylam Pharmaceuticals Inc|Grant or research support-Preventice Solutions|Grant or research support-Novo Nordisk AS|Grant or research support-Ionis Pharmaceuticals Inc|Grant or research support-Eidos Therapeutics Inc|Grant or research support-Abbott Diagnostic Scarborough Inc|Grant or research support-Alexion Pharmaceuticals Inc|Grant or research support-Bristol Myers Squibb Co/BMS|Grant or research support-Bayer HealthCare Pharmaceuticals|Grant or research support-AstraZeneca AB (Sweden)
Jonathan Moreno, MD, PhD
Assistant Professor
WashU Medicine
St. Louis, MO
Faculty
Nothing to disclose
Faculty Photos
Naoka Murakami, MD, FASN, FAST
Assistant Professor of Medicine
WashU Medicine
St. Louis, MO
Faculty
Grant or research support-Transplantation Society|Other relevant financial or material interests-Elsevier/Publisher (*)|Other relevant financial or material interests-Regeneron (*)
Joshua David Newman, MD
Barnes-Jewish Hospital
St. Louis, MO
Faculty
Michael Slade, MD
Assistant Professor of Medicine Division of Oncology, Leukemia and Bone Marrow Transplant
WashU Medicine
St. Louis, MO
Faculty
Grant or research support-AbbVie Inc|Grant or research support-AstraZeneca Pharmaceuticals LP|Grant or research support-BeOne Medicines (formerly BeiGene Ltd)|Grant or research support-Bristol Myers Squibb Co/BMS|Grant or research support-Celgene Corporation|Grant or research support-CellCentric|Grant or research support-Cures Within Reach|Grant or research support-Genentech Inc|Grant or research support-Menarini Silicon Biosystems|Grant or research support-Multiple Myeloma Research Consortium, LLC|Grant or research support-Natera, Inc.|Grant or research support-NeoImmuneTech|Grant or research support-Pfizer Inc|Grant or research support-Phase Genomics|Grant or research support-Sanofi US Services Inc|Speakers Bureau-Curio (*)|Speakers Bureau-Roche Bioscience (*)
Faculty Photos
Justin M. Vader, MD, FACC, FHFSA
Professor of Medicine, Cardiovascular Division
WashU Medicine
St. Louis, MO
Faculty
Other relevant financial or material interests|Grant or research support-Novo Nordisk AS|Grant or research support-Ancora Heart Inc|Grant or research support-Cytokinetics Inc|Grant or research support-Endotronix
Kinsey Walker, BSN, RN
Nurse Coordinator
WashU Medicine
St. Louis, MO
Faculty
Nothing to disclose
Faculty Photos
Elizabeth Blaney, MD
Associate Professor of Medicine
Barnes-Jewish Hospital
St Louis, MO
Faculty, Other Planning Committee Member
Nothing to disclose
Stefanie Geisler, MD
Assistant Professor
WashU Medicine
St. Louis, MO
Faculty, Other Planning Committee Member
Speakers Bureau-AbbVie Inc (*)|Other relevant financial or material interests-SIRONAX USA INC. (*)
Andrew M. Kates, MD, FACC
Professor of Medicine
WashU Medicine
St. Louis, MO
Faculty, Other Planning Committee Member
Grant or research support-Eidos Therapeutics Inc
Tingting Li, MD, MSCI
Professor of Medicine
WashU Medicine
St. Louis, MO
Faculty, Other Planning Committee Member
Other relevant financial or material interests-Calliditas Therapeutics (*)|Other relevant financial or material interests-Curio Science, LLC (*)|Other relevant financial or material interests-GlaxoSmithKline/GSK|Other relevant financial or material interests-Novartis (*)|Other relevant financial or material interests-Travere Therapeutics Inc (*)|Other relevant financial or material interests-Vera Therapeutics (*)|Grant or research support-Novartis Pharmaceuticals Corporation|Grant or research support-Vertex Pharmaceuticals Inc|Grant or research support-Calliditas Therapeutics|Grant or research support-Dimerix|Grant or research support-Asahi Kasei Therapeutics, AB|Other relevant financial or material interests-Asahi Kasei Therapeutics, AB (*)
Ann C Mahoney, RN
RN Coordinator
WashU Medicine
St. Louis, MO
Faculty, Other Planning Committee Member
Consulting Fee-AstraZeneca (Any division)
Angela Robichaud , PharmD
Clinical Pharmacist
BJC
St. Louis, MO
Faculty, Pharmacy Planner
Nothing to disclose

Saturday, February 27, 2027

Amyloidosis 2027

Registration and Continental Breakfast
7:15AM - 8:00AM

Welcome and Introduction: Joshua D. Mitchell, MD, MSCI, Keith Stockerl-Goldstein, MD, and Molly Rater, ANP
8:00AM - 8:05AM

SESSION I - IMPROVING RECOGNITION AND CLARIFYING THE DIAGNOSIS

Who Are We Still Missing? Disparities and Delays in the Diagnosis of Amyloidosis: Frederick L. (Rick) Ruberg, MD
8:05AM - 8:25AM

When the Tests Disagree: Mass Spectrometry Typing, Bystander Proteins, and Amyloid Mimics: Ellen D. McPhail, MD
8:25AM - 8:45AM

ATTR Patient Journey: Bruce Janssen with Joshua D. Mitchell, MD, MSCI and Keith Stockerl-Goldstein, MD
8:45AM - 9:00AM

Amyloidosis and the Kidney: Naoka Murakami, MD, PhD
9:20AM - 9:40AM

Panel Discussion: Diagnostic Traps in 2027: Bone Scans, Light Chains, and Everything In BetweenEllen D. McPhail, MD, Frederick L. Ruberg, MD, Stefanie Geisler, MD, Naoka Murakami, MD, PhD, Joshua D. Mitchell, MD, MSCI
9:40AM - 9:50AM

Refreshment Break & Exhibits
9:50AM - 10:10AM

SESSION II - ADVANCED IMAGING AND BIOLOGICAL INSIGHTS

Visualizing the Disease and the Response to Treatment: Advanced Imaging in Amyloidosis: Sharmila Dorbala, MD, MPH
10:10AM - 10:30AM

Beyond the Fibril: Inflammation and Fibrosis in Cardiac Amyloidosis: Joshua D. Mitchell, MD, MSCI
10:30AM - 10:50AM

Discussion: Amyloidosis Imaging and PathophysiologySharmila Dorbala, MD, MPH and Joshua D. Mitchell, MD, MSCI
10:50AM - 11:00AM

SESSION III - TREATING ATTR AMYLOIDOSIS

Cardiac Amyloidosis Patient Presentation: TBD
11:00AM - 11:05AM

Approved Therapy for ATTR-CM in 2027: Stabilize, Silence, or Both? Andrew M. Kates, MD, FACC
11:05AM - 11:25AM

The Next Generation: Gene Editing, Near-Complete Silencing, and Amyloid Depletion: Mathew Maurer, MD
11:25AM - 11:45AM

Panel Discussion: Treat-to-Trajectory: Sequencing, Combination Therapy, and How We MonitorMathew Maurer, MD, Andrew M. Kates, MD, FACC, Joshua D. Mitchell, MD, MSCI, Jonathan D. Moreno, MD, PhD, Justin M. Vader, MD
11:45AM - 12:00PM

Lunch (provided)
12:00PM - 1:00PM

SESSION IV - TREATING AL AMYLOIDOSIS

AL Amyloidosis Patient Presentation: TBD
1:00PM - 1:05PM

Reading the Light Chains: Diagnostic Work-Up and Response Assessment in AL Amyloidosis: Keith Stockerl-Goldstein, MD
1:05PM - 1:25PM

Frontline Therapy for AL Amyloidosis in 2027: Michael Slade, MD
1:25PM - 1:45PM

Panel Discussion: AL Amyloidosis from First Suspicion to Deep ResponseHeather J. Landau, MD (pending), Keith Stockerl-Goldstein, MD, Michael Slade, MD, Naoka Murakami, MD, PhD
2:05PM - 2:15PM

Refreshment Break & Exhibits
2:15PM - 2:25PM

SESSION V - CARING FOR THE WHOLE PATIENT

Cardiac Amyloidosis Patient Presentation : TBD
2:25PM - 2:30PM

Cardiovascular Management Beyond Amyloid-Directed Therapy: Justin M. Vader, MD, FACC, FHFSA
2:30PM - 2:50PM

Gastrointestinal Manifestations and Nutrition in Amyloidosis: Elizabeth J. Blaney, MD
2:50PM - 3:10PM

Nuts and Bolts: Getting Patients on Therapy, Navigating Insurance, and Optimizing Care for Veterans: Ann Mahoney, RN and Jonathan D. Moreno, MD, PhD
3:10PM - 3:30PM

Panel Discussion: Multidisciplinary Care of Systemic Amyloidosis in 2027Elizabeth J. Blaney, MD, Stefanie Geisler, MD, Tingting Li, MD, MSCI, Keith Stockerl-Goldstein, MD, Justin M. Vader, MD
3:30PM - 3:40PM

Adjourn CME program / Short break before Non-CME Portion
3:40PM - 3:45PM

The following session is non-CME accredited. Healthcare providers are welcome to attend

Welcome, Question & Answer Breakout Session: Open to Patients, Family Members & Caregivers touched by amyloidosis and their families which will allow them the opportunity to ask questions of various medical providers and network
3:45PM - 4:20PM

Adjourn
4:20PM - 4:20PM

If you are with a company and would like to exhibit or provide an educational grant for this educational program, please contact Stacy Partrich at [email protected] 



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Washington University School of Medicine in St. Louis 
660 S. Euclid
MSC 8063-029-2219
St. Louis, MO 63110

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Phone: 314-362-6891 or 800-325-9862  

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